Currently, there are several screening methods for Down syndrome, each with varying degrees of accuracy. Quad Test is a popular, simple, modern screening technique for biochemical markers in maternal blood with an accuracy of up to 86%.
“If you are interested in Down syndrome screening, please contact Intouch Medicare for more information.”
Interesting facts about Quad Test
Quad Test involves the analysis of 4 biochemical markers in maternal blood: Alpha fetoprotein (AFP), Unconjugated estriol (uE3), Beta-human chrorionic gonadotropin (free β-hCG), and Dimeric Inhibin-A.
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This is to ascertain whether the fetus is at risk of Down syndrome.
Quad Test or Quadruple Test is an effective second-trimester screening method for Down syndrome. It is usually performed between weeks 15 and 20 of pregnancy (14 and 18 weeks is the optimal gestational age).
The doctor gives advice on Down syndrome screening to expectant woman less than 18 weeks into pregnancy.
If the expectant woman agrees to Down syndrome screening, an ultrasound scan is then performed to confirm the gestational age.
Approximately 3-5 ml of blood of the expectant woman is and sent to the laboratory for examination.
The test results can be divided into 2 groups: high-risk group with a risk rating of 1:200 or more and low-risk group with a risk rating of less than 1:200.
1:250 is the criterion used to classify risks as
Reference: Maternal and Child Health, Bureau of Health Promotion, Department of Health
Quad Test cannot identify the gender of the fetus as it only involves the analysis of biochemical markers in the blood.
NIPT (Non-invasive prenatal test) or Nifty is the superior screening test due to the fact that it is based on a laboratory analysis of fetal DNA released into the mother’s bloodstream and the identification of number of chromosomes of the fetus. It is a more recent, superior testing screening technique compared to other methods.
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Quad Test or Quadruple Test is an effective second-trimester screening method. It should be performed between weeks 14 and 18 of pregnancy.
Interesting article
Comprehensive Methods for Down Syndrome Screening Every Expectant Mother Should Know
What is the NIFTY Test? Why Should You Get It and What Are the Steps Involved?
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Composer: Nonlapan Pitagsalee, M.D.
Last edited : 24/10/2024
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