Currently, there are several screening methods for Down syndrome, each with varying degrees of accuracy. Quad Test is a popular, simple, modern screening technique for biochemical markers in maternal blood with an accuracy of up to 86%.
“If you are interested in Down syndrome screening, please contact Intouch Medicare for more information.”
Interesting facts about Quad Test
What is Quad Test?
Quad Test or Quadruple Test is an effective second-trimester screening method for Down syndrome.
The optimal gestational age for the Quad Test, which involves the analysis of 4 biochemical markers, is between 14 and 18 weeks.
More information of other screening methods for Down syndrome: Down syndrome screening methods expectant mothers should know
What biochemical markers are analyzed in Quad Test?
Quad Test involves the analysis of 4 biochemical markers in maternal blood: Alpha fetoprotein (AFP), Unconjugated estriol (uE3), Beta-human chrorionic gonadotropin (free β-hCG), and Dimeric Inhibin-A.
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This is to ascertain whether the fetus is at risk of Down syndrome.
What is the optimal gestational age for Quad Test?
Quad Test or Quadruple Test is an effective second-trimester screening method for Down syndrome. It is usually performed between weeks 15 and 20 of pregnancy (14 and 18 weeks is the optimal gestational age).

Price of Quad Test
- Price: 2,890 Baht
Note: Professional fee and service charge are included.
“The maternal blood is used in this test. You are not required to fast or refrain from eating or drinking. It takes only 7 days to obtain the results.”
Accuracy of Quad Test
The detection rate of Quad Test is 86%.
Procedures and methods
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The doctor gives advice on Down syndrome screening to expectant woman less than 18 weeks into pregnancy.
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If the expectant woman agrees to Down syndrome screening, an ultrasound scan is then performed to confirm the gestational age.
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Approximately 3-5 ml of blood of the expectant woman is and sent to the laboratory for examination.
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Result notification
The test results can be divided into 2 groups: high-risk group with a risk rating of 1:200 or more and low-risk group with a risk rating of less than 1:200.
1:250 is the criterion used to classify risks as
Reference: Maternal and Child Health, Bureau of Health Promotion, Department of Health
Low risk
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A risk rating of less than 1:250, such as 1:300 or 1:500, indicates that you are in the “low risk group” and that the likelihood of the fetus having Down syndrome is low.
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There is less need for prenatal diagnosis (PND).
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A low risk rating does not guarantee that the fetus is normal as Down syndrome can still be found in some pregnant women.
High risk
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A risk rating of 1:250 or more, such as 1:200, 1:100, indicates that you are in the “high risk group” and that the likelihood of the fetus having Down syndrome is high.
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The pregnant mother will be recommended to have a prenatal diagnostic procedure (PND), such as amniocentesis.
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A high risk rating does not always indicate that the fetus will develop Down syndrome.
Frequently asked questions
Can Quad Test be used to identify the fetal gender?
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Quad Test cannot identify the gender of the fetus as it only involves the analysis of biochemical markers in the blood.
NIPT and Quad Test, which is better?
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NIPT (Non-invasive prenatal test) or Nifty is the superior screening test due to the fact that it is based on a laboratory analysis of fetal DNA released into the mother’s bloodstream and the identification of number of chromosomes of the fetus. It is a more recent, superior testing screening technique compared to other methods.
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When to do a Quad Test?
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Quad Test or Quadruple Test is an effective second-trimester screening method. It should be performed between weeks 14 and 18 of pregnancy.
Get screening for Down syndrome and other abnormalities for your peace of mind.
Feel free to contact Intouch Medicare through any channel. Our staff are ready to help and offer you guidance and attention.
You can obtain more details about the Quad Test offered by or Intouch Medicare Clinic by typing “quad test clinic near me” into Google search.
Interesting Article
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Comprehensive Methods for Down Syndrome Screening Every Expectant Mother Should Know
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What is the NIFTY Test? Why Should You Get It and What Are the Steps Involved?
For more info and make appointment
Hot Line 081-562-7722

Suphansa Niawbupha ,M.D.
General Practitioner
Latest edit : 18/01/2024
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